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Product Specification
【ProductName】

KAT2A Antibody Blocking Peptide

【Cat NO.】

K111139P-Ag

【Source】

Synthetic

【Storage】

Store at -20℃,2 years.Avoid freeze/thaw cycles.

【Appearance】

Lyophilized powder

【Swiss Prot】

Q92830

【Gene ID】

2648

【Application】

Blocking Peptide of K111139P Antibody

【Purification】

HPLC

【Activity】

Not tested

【Note】

Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging.

Background:

Protein lysine acyltransferase that can act as a acetyltransferase, glutaryltransferase or succinyltransferase, depending on the context (PubMed:29211711). Acts as a histone lysine succinyltransferase: catalyzes succinylation of histone H3 on ’Lys-79’ (H3K79succ), with a maximum frequency around the transcription start sites of genes (PubMed:29211711). Succinylation of histones gives a specific tag for epigenetic transcription activation (PubMed:29211711). Association with the 2-oxoglutarate dehydrogenase complex, which provides succinyl-CoA, is required for histone succinylation (PubMed:29211711). In different complexes, functions either as an acetyltransferase (HAT) or as a succinyltransferase: in the SAGA and ATAC complexes, acts as a histone acetyltransferase (PubMed:17301242, PubMed:19103755, PubMed:29211711). Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles (PubMed:17301242, PubMed:19103755). Acetylation of histones g