 |
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|---|---|---|
| 【ProductName】 |
ENPP2 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K111498P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q13822 |
|
| 【Gene ID】 |
5168 |
|
| 【Application】 |
Blocking Peptide of K111498P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
Hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids (PubMed:15769751， PubMed:26371182， PubMed:27754931， PubMed:14500380， PubMed:12354767，). Major substrate is lysophosphatidylcholine (PubMed:12176993， PubMed:27754931， PubMed:14500380). Also can act on sphingosylphosphorylcholine producing sphingosine-1-phosphate， a modulator of cell motility (PubMed:14500380). Can hydrolyze， in vitro， bis-pNPP， to some extent pNP-TMP， and barely ATP (PubMed:15769751， PubMed:12176993). Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation (PubMed:11559573). Stimulates migration of melanoma cells， probably via a pertussis toxin-sensitive G protein (PubMed:1733949). May have a role in induction of parturition (PubMed:12176993). Possible involvement in cell proliferation and adipose tissue development (