 |
||
|---|---|---|
| 【ProductName】 |
EIF4EBP1 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K111622P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q13541 |
|
| 【Gene ID】 |
1978 |
|
| 【Application】 |
Blocking Peptide of K111622P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
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Background：
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E)， which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5’ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling， resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq， Jul 2008]