Anti-LIN28 Polyclonal Antibody
Cat: K010041P
Summary:
| 【Product name】：Anti-LIN28 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79727 | 【Swiss Prot】：Q9H9Z2 |
| 【Observed】：28 kDa | |
| 【Tested applications】：WB,IHC,IF | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human LIN28 | |
| 【Public Immunogen Range】：100-209aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
Verified picture:
Western blot analysis with LIN28 antibody diluted at 1:700;Lane: T47D.