Anti-COPS4 Polyclonal Antibody
Cat: K112356P
Summary:
| 【Product name】：Anti-COPS4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51138 | 【Swiss Prot】：Q9BT78 |
| 【Observed】：46kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human COPS4 | |
| 【Public Immunogen Range】：61-407aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with COPS4 antibody diluted at 1:2000;Lane: NIH3T3.
Immunohistochemistry of paraffin-embedded human renal cancer with COPS4 antibody diluted at 1:100.