Anti-SIRT7 Polyclonal Antibody
Cat: K112359P
Summary:
| 【Product name】：Anti-SIRT7 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51547 | 【Swiss Prot】：Q9NRC8 |
| 【Observed】：49kDa | |
| 【Tested applications】：IHC,WB,ELISA | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SIRT7 | |
| 【Public Immunogen Range】：51-401aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Verified picture:
Western blot analysis with SIRT7 antibody diluted at 1:3000;Lane: Vero.
Immunohistochemistry of paraffin-embedded human breast cancer with SIRT7 antibody diluted at 1:100.