Anti-MBD4 Polyclonal Antibody
Cat: K112389P
Summary:
| 【Product name】：Anti-MBD4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8930 | 【Swiss Prot】：O95243 |
| 【Observed】：70kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human MBD4 | |
| 【Public Immunogen Range】：1-574aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
Verified picture:
Western blot analysis with MBD4 antibody diluted at 1:2000;Lane: HeLa,Jurkat,THP-1,HMC1,MCF7.