Anti-COMMD1 Polyclonal Antibody - SAlexa Fluor 488
Cat: K112393P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-COMMD1 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：150684 | 【Swiss Prot】：Q8N668 |
| 【Observed】：19kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human COMMD1 | |
| 【Public Immunogen Range】：1-191aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity: Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.
Verified picture: