Anti-EARS2 Polyclonal Antibody
Cat: K112456P
Summary:
| 【Product name】：Anti-EARS2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：124454 | 【Swiss Prot】：Q5JPH6 |
| 【Observed】：58kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human EARS2 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with EARS2 antibody diluted at 1:3000;Lane: K-562,T47d,HEK293,Jurkat.
Immunohistochemistry of paraffin-embedded human testis cancer with EARS2 antibody diluted at 1:50.