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Anti-IL1R2 Polyclonal Antibody
Cat: K112479P
Summary:
【Product name】:Anti-IL1R2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:7850 【Swiss Prot】:P27930
【Tested applications】:IHC
【Recommended dilution】:IHC 1:25-100.
【Immunogen】:Recombinant protein of human IL1R2
【Public Immunogen Range】:1-350aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
Verified picture:
Immunohistochemistry of paraffin-embedded human liver cancer with IL1R2 antibody diluted at 1:50.
Immunohistochemistry of paraffin-embedded human pancreatic cancer with IL1R2 antibody diluted at 1:50.
Immunohistochemistry of paraffin-embedded human testis cancer with IL1R2 antibody diluted at 1:50.