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Anti-WDFY1 Polyclonal Antibody - SAlexa Fluor 488
Cat: K112482P - SAlexa Fluor 488
Summary:
【Product name】:Anti-WDFY1 Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:57590 【Swiss Prot】:Q8IWB7
【Observed】:56kDa
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human WDFY1
【Public Immunogen Range】:1-350aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines (PubMed:25736436).
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