Anti-H2BC3 Polyclonal Antibody
Cat: K112519P
Summary:
| 【Product name】：Anti-H2BC3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3018 | 【Swiss Prot】：P33778 |
| 【Observed】：17kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human H2BC3 | |
| 【Public Immunogen Range】：1-127aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Verified picture:
Western blot analysis with H2BC3 antibody diluted at 1:1000;Lane: HeLa,Jurkat,293T,THP-1,PC-3M-IE8,U937.
Immunohistochemistry of paraffin-embedded human breast cancer with H2BC3 antibody diluted at 1:50.
Immunohistochemistry of paraffin-embedded human prostate cancer with H2BC3 antibody diluted at 1:50.