Anti-CLK1 Polyclonal Antibody
Cat: K112552P
Summary:
| 【Product name】：Anti-CLK1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1195 | 【Swiss Prot】：P49759 |
| 【Observed】：50/60kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human CLK1 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with CLK1 antibody diluted at 1:2000;Lane: HepG2,MCF7,HeLa,Jurkat.
Immunohistochemistry of paraffin-embedded human breast cancer with CLK1 antibody diluted at 1:200.