Anti-H3-5 Polyclonal Antibody - SAlexa Fluor 488
Cat: K112570P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-H3-5 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：440093 | 【Swiss Prot】：Q6NXT2 |
| 【Observed】：18kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human H3-5 | |
| 【Public Immunogen Range】：1-136aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Hominid-specific H3.5/H3F3C preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes.
Verified picture: