Anti-XIAP Polyclonal Antibody - HRP
Cat: K010057P - HRP
Summary:
| 【Product name】：Anti-XIAP Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：331 | 【Swiss Prot】：P98170 |
| 【Tested applications】：IHC,IF | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of mouse XIAP | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
X-linked inhibitor of apoptosis protein (XIAP) is a protein that stops apoptotic cell death. XIAP is a member of the inhibitor of apoptosis family of proteins (IAP). XIAP stops apoptotic cell death that is induced either by viral infection or by overproduction of caspases. Caspases are the enzymes primarily responsible for cell death. XIAP binds to and inhibits caspase 3, 7 and 9. The BIR2 domain of XIAP inhibits caspase 3 and 7, while BIR3 binds to and inhibits caspase 9.
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