Anti-KANK2 Polyclonal Antibody
Cat: K010061P
Summary:
| 【Product name】：Anti-KANK2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：25959 | 【Swiss Prot】：Q63ZY3 |
| 【Observed】：100kDa | |
| 【Tested applications】：ELISA,WB,IHC,IF | |
| 【Recommended dilution】：WB 1:500-3000. IHC 1:50-500. IF 1:50-500. | |
| 【Immunogen】：Recombinant protein of human KANK2 | |
| 【Public Immunogen Range】：1-215aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus. May be involved in promotion of cell proliferation.
Verified picture:
Western blot analysis with KANK2 antibody diluted at 1:500;Lane: Mouse heart Mouse lung.
Immunohistochemistry of paraffin-embedded human kidney using KANK2 antibody diluted at 1:200.
Immunofluorescence analysis of HepG2 cells using KANK2 antibody diluted at 1:200.