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Anti-KANK2 Polyclonal Antibody - SAlexa Fluor 640
Cat: K010061P - SAlexa Fluor 640
Summary:
【Product name】:Anti-KANK2 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:25959 【Swiss Prot】:Q63ZY3
【Observed】:100kDa
【Tested applications】:ELISA,WB,IHC,IF
【Recommended dilution】:WB 1:500-3000. IHC 1:50-500. IF 1:50-500.
【Immunogen】:Recombinant protein of human KANK2
【Public Immunogen Range】:1-215aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus. May be involved in promotion of cell proliferation.
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