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Anti-COQ6 Polyclonal Antibody - SAlexa Fluor 640
Cat: K112609P - SAlexa Fluor 640
Summary:
【Product name】:Anti-COQ6 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:51004 【Swiss Prot】:Q9Y2Z9
【Observed】:51kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human COQ6
【Public Immunogen Range】:1-350aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-hexaprenyl-4-hydroxybenzoic acid (HHB) to 3-hexaprenyl-4,5-dihydroxybenzoic acid (DHHB). The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6 (By similarity).Is able to perform the deamination reaction at C4 of 3-hexaprenyl-4-amino-5-hydroxybenzoic acid (HHAB) to produce DHHB when expressed in yeast cells lacking COQ9, even if utilization of para-aminobenzoic acid (pABA) involving C4-deamination seems not to occur in bacteria, plants and mammals, where only C5 hydroxylation of HHB has been shown (PubMed:26260787).
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