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Anti-PDE1C Polyclonal Antibody - HRP
Cat: K112726P - HRP
Summary:
【Product name】:Anti-PDE1C Polyclonal Antibody - HRP 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:5137 【Swiss Prot】:Q14123
【Observed】:72kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200
【Immunogen】:Recombinant protein of human PDE1C
【Public Immunogen Range】:285-635aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
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