Anti-TJP2 Polyclonal Antibody
Cat: K112748P
Summary:
| 【Product name】：Anti-TJP2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：9414 | 【Swiss Prot】：Q9UDY2 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of Human TJP2 | |
| 【Public Immunogen Range】：40-90/1190aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded human colorectal cancer with TJP2 antibody diluted at 1:50.