Anti-SPTAN1 (Cleaved-Asp1185) Polyclonal Antibody
Cat: K112759P
Summary:
| 【Product name】：Anti-SPTAN1 (Cleaved-Asp1185) Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6709 | 【Swiss Prot】：Q13813 |
| 【Observed】：150/285kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of Human SPTAN1 (Cleaved-Asp1185) | |
| 【Public Immunogen Range】：1180-1230/2472aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with SPTAN1 (Cleaved-Asp1185) antibody diluted at 1:3000;Lane: Mouse brain,Rat brain.
Immunohistochemistry of paraffin-embedded human colorectal cancer with SPTAN1 (Cleaved-Asp1185) antibody diluted at 1:50.