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Anti-CEP170 Polyclonal Antibody - SAlexa Fluor 568
Cat: K112772P - SAlexa Fluor 568
Summary:
【Product name】:Anti-CEP170 Polyclonal Antibody - SAlexa Fluor 568 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9859 【Swiss Prot】:Q5SW79
【Tested applications】:IHC
【Recommended dilution】:IHC 1:25-100.
【Immunogen】:A synthetic peptide of Human CEP170
【Public Immunogen Range】:900-950/1584aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined.
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