Anti-TSC2 Polyclonal Antibody
Cat: K112838P
Summary:
| 【Product name】：Anti-TSC2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7249 | 【Swiss Prot】：P49815 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human TSC2 | |
| 【Public Immunogen Range】：1245-1295/1807aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Verified picture:
Immunohistochemistry of paraffin-embedded human colorectal cancer with TSC2 antibody diluted at 1:50.