Anti-BMI1 Polyclonal Antibody
Cat: K010085P
Summary:
| 【Product name】：Anti-BMI1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：648 | 【Swiss Prot】：P35226 |
| 【Observed】：37kDa | |
| 【Tested applications】：ELISA,IF,IHC,IP,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:20-200. IF 1:20-200. | |
| 【Immunogen】：Recombinant protein of human BMI1 | |
| 【Public Immunogen Range】：1-326aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody 10832-1-AP detected proteins of 45-48kda, which may include phosphorylated isoforms of the protein.
Verified picture:
Western blot analysis with BMI1 antibody diluted at 1:1000;Lane: U937.
Immunohistochemistry of paraffin-embedded human liver cancer with BMI1 antibody diluted at 1:50.
Immunofluorescence analysis of HepG2 using BMI1 antibody diluted at 1:50.