Anti-TSC2 Polyclonal Antibody - Biotin
Cat: K112922P - Biotin
Summary:
| 【Product name】：Anti-TSC2 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7249 | 【Swiss Prot】：P49815 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human TSC2 | |
| 【Public Immunogen Range】：630-680/1807aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
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