Anti-DOCK1 Polyclonal Antibody - HRP
Cat: K112929P - HRP
Summary:
| 【Product name】：Anti-DOCK1 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：1793 | 【Swiss Prot】：Q14185 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human DOCK1 | |
| 【Public Immunogen Range】：1430-1480/1865aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen ;Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1
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