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Anti-ANAPC1 Polyclonal Antibody
Cat: K112931P
Summary:
【Product name】:Anti-ANAPC1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:64682 【Swiss Prot】:Q9H1A4
【Tested applications】:IHC
【Recommended dilution】:IHC 1:25-100.
【Immunogen】:A synthetic peptide of human ANAPC1
【Public Immunogen Range】:550-600/1944aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Verified picture:
Immunohistochemistry of paraffin-embedded Human renal cancer with ANAPC1 antibody diluted at 1:50.