Anti-ITPR1 Polyclonal Antibody - Biotin
Cat: K112946P - Biotin
Summary:
| 【Product name】：Anti-ITPR1 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3708 | 【Swiss Prot】：Q14643 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human ITPR1 | |
| 【Public Immunogen Range】：1150-1200/2758aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate;Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1;Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
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