Anti-PYGB Polyclonal Antibody
Cat: K112984P
Summary:
| 【Product name】：Anti-PYGB Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：5834 | 【Swiss Prot】：P11216 |
| 【Observed】：100kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human PYGB | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
Verified picture:
Western blot analysis with PYGB antibody diluted at 1:2000;Lane: A549,Mouse brain,Mouse heart,Mouse lung,Rat heart.
Immunohistochemistry of paraffin-embedded human pancreatic cancer with PYGB antibody diluted at 1:100.