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Anti-CRHBP Polyclonal Antibody
Cat: K112998P
Summary:
【Product name】:Anti-CRHBP Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1393 【Swiss Prot】:P24387
【Tested applications】:IHC
【Recommended dilution】:IHC 1:25-100.
【Immunogen】:Recombinant protein of human CRHBP
【Public Immunogen Range】:1-323aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Verified picture:
Immunohistochemistry of paraffin-embedded human colorectal cancer with CRHBP antibody diluted at 1:50.
Immunohistochemistry of paraffin-embedded human pancreatic cancer with CRHBP antibody diluted at 1:50.