Anti-HADHA Polyclonal Antibody
Cat: K113011P
Summary:
| 【Product name】：Anti-HADHA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3030 | 【Swiss Prot】：P40939 |
| 【Observed】：73/75kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human HADHA | |
| 【Public Immunogen Range】：414-764aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
Verified picture:
Western blot analysis with HADHA antibody diluted at 1:3000;Lane: HepG2,SHSY5Y,,HeLa,Jurkat,RAW264.7,NIH3T3,K562,THP1,SW480,PC3,U251,293T,MCF-7,Mouse heart,Mouse kidney,Mouse liver,Rat heart.
Immunohistochemistry of paraffin-embedded human renal cancer with HADHA antibody diluted at 1:50.