Anti-GPR49/LGR5 Polyclonal Antibody
Cat: K010092P
Summary:
| 【Product name】：Anti-GPR49/LGR5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8549 | 【Swiss Prot】：O75473 |
| 【Tested applications】：ELISA,IHC,WB,FCM | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:100-500.FCM 1μg/Test.ELISA 1:5000-10000. | |
| 【Immunogen】：A synthetic peptide of human GPR49/LGR5 | |
| 【Public Immunogen Range】：211-310/907aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Verified picture:
Western blot analysis with GPR49/LGR5 antibody diluted at 1:1000;Lane: Mouse Cerebrum Mouse Stomach Mouse Colon.
Immunohistochemistry of paraffin-embedded mouse brain tissue with GPR49 antibody diluted at 1:400.