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Anti-PLA1A Polyclonal Antibody - SAlexa Fluor 660
Cat: K113066P - SAlexa Fluor 660
Summary:
【Product name】:Anti-PLA1A Polyclonal Antibody - SAlexa Fluor 660 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:51365 【Swiss Prot】:Q53H76
【Observed】:48kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:2000-5000. IHC 1:25-100.
【Immunogen】:Recombinant protein of human PLA1A
【Public Immunogen Range】:1-350aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling (PubMed:10196188).Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production (By similarity).Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein (By similarity).
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