Anti-CMTM8 Polyclonal Antibody - SAlexa Fluor 633
Cat: K113113P - SAlexa Fluor 633
Summary:
| 【Product name】：Anti-CMTM8 Polyclonal Antibody - SAlexa Fluor 633 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：152189 | 【Swiss Prot】：Q8IZV2 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human CMTM8 | |
| 【Public Immunogen Range】：110-160/173aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
CMTM8, also known as CKLFSF8, is a member of the chemokine-like factor superfamily (CKLFSF).Proteins of this family share similarity with both the chemokine and the transmembrane 4 superfamilies. CMTM8 is an attenuator of EGF-induced signaling (PMID: 16263120).Overexpression of CMTM8 accelerates ligand-induced clearance of EGFR from the cell surface and induces apoptosis via caspase-dependent and -independent pathways (PMID: 17149703).An alternative splice form of CMTM8, CMTM8-v2, arises from a deletion of exon 2. CMTM8-v2 maintains the ability to induce apoptosis (PMID: 17681841).
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