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Anti-NRTN Polyclonal Antibody - Biotin
Cat: K113118P - Biotin
Summary:
【Product name】:Anti-NRTN Polyclonal Antibody - Biotin 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:4902 【Swiss Prot】:Q99748
【Observed】:22kDa
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human NRTN
【Public Immunogen Range】:30-80/197aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.
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