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Anti-CFL2 Polyclonal Antibody - SAlexa Fluor 640
Cat: K113146P - SAlexa Fluor 640
Summary:
【Product name】:Anti-CFL2 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:1073 【Swiss Prot】:Q9Y281
【Observed】:19kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:A synthetic peptide of human CFL2
【Public Immunogen Range】:30-80/166aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
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