Anti-SELENOT Polyclonal Antibody - Biotin
Cat: K113158P - Biotin
Summary:
| 【Product name】：Anti-SELENOT Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51714 | 【Swiss Prot】：P62341 |
| 【Observed】：19kDa | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human SELENOT | |
| 【Public Immunogen Range】：1-51/194aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Selenoprotein with thioredoxin reductase-like oxidoreductase activity (By similarity).Protects dopaminergic neurons against oxidative stress ans cell death (PubMed:26866473).Involved in ADCYAP1/PACAP-induced calcium mobilization and neuroendocrine secretion (By similarity).Plays a role in fibroblast anchorage and redox regulation (By similarity).In gastric smooth muscle, modulates the contraction processes through the regulation of calcium release and MYLK activation (By similarity).In pancreatic islets, involved in the control of glucose homeostasis, contributes to prolonged ADCYAP1/PACAP-induced insulin secretion (By similarity).
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