Anti-CD82 Polyclonal Antibody - SAlexa Fluor 488
Cat: K113205P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-CD82 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3732 | 【Swiss Prot】：P27701 |
| 【Observed】：36-50kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CD82 | |
| 【Public Immunogen Range】：180-230/267aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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