Anti-BTK Polyclonal Antibody
Cat: K113219P
Summary:
| 【Product name】：Anti-BTK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：695 | 【Swiss Prot】：Q06187 |
| 【Observed】：76kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human BTK | |
| 【Public Immunogen Range】：10-360aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with BTK antibody diluted at 1:2000;Lane: 293T,HeLa,U937,Raji,K-562,L-02.