Anti-FGD5 Polyclonal Antibody
Cat: K113220P
Summary:
| 【Product name】：Anti-FGD5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：152273 | 【Swiss Prot】：Q6ZNL6 |
| 【Observed】：178kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human FGD5 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
Verified picture:
Immunohistochemistry of paraffin-embedded Human renal cancer with FGD5 antibody diluted at 1:100.
Western blot analysis with FGD5 antibody diluted at 1:2000;Lane: Mouse brain.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with FGD5 antibody diluted at 1:100.