Anti-NOS1AP Polyclonal Antibody - SAlexa Fluor 660
Cat: K113245P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-NOS1AP Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9722 | 【Swiss Prot】：O75052 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human NOS1AP | |
| 【Public Immunogen Range】：150-500aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity).In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation (PubMed:33523862).
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