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Anti-ABCE1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K113257P - SAlexa Fluor 640
Summary:
【Product name】:Anti-ABCE1 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:6059 【Swiss Prot】:P61221
【Observed】:67kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:2000-5000. IHC 1:25-100.
【Immunogen】:Recombinant protein of human ABCE1
【Public Immunogen Range】:250-600aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
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