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Anti-CAPN3 Polyclonal Antibody - SAlexa Fluor 405
Cat: K113267P - SAlexa Fluor 405
Summary:
【Product name】:Anti-CAPN3 Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:825 【Swiss Prot】:P20807
【Observed】:85kDa
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-3000.
【Immunogen】:Recombinant protein of human CAPN3
【Public Immunogen Range】:1-309aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
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