Anti-AZI2 Polyclonal Antibody
Cat: K113463P
Summary:
| 【Product name】：Anti-AZI2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：64343 | 【Swiss Prot】：Q9H6S1 |
| 【Observed】：52kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human AZI2 | |
| 【Public Immunogen Range】：342-392/392aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity (PubMed:14560022, PubMed:21931631).Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization (PubMed:14560022, PubMed:21931631).Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1 (PubMed:14560022, PubMed:21931631).Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B (PubMed:14560022, PubMed:21931631).Participates in IFNB promoter activation via TICAM1 (PubMed:15611223).
Verified picture:
Western blot analysis with AZI2 antibody diluted at 1:2000;Lane: HepG2,U937,U-251MG.
Immunohistochemistry of paraffin-embedded Human endometrial cancer with AZI2 antibody diluted at 1:50.