Anti-AZI2 Polyclonal Antibody - HRP
Cat: K113463P - HRP
Summary:
| 【Product name】：Anti-AZI2 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：64343 | 【Swiss Prot】：Q9H6S1 |
| 【Observed】：52kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human AZI2 | |
| 【Public Immunogen Range】：342-392/392aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity (PubMed:14560022, PubMed:21931631).Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization (PubMed:14560022, PubMed:21931631).Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1 (PubMed:14560022, PubMed:21931631).Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B (PubMed:14560022, PubMed:21931631).Participates in IFNB promoter activation via TICAM1 (PubMed:15611223).
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