Anti-PLD3 Polyclonal Antibody
Cat: K113466P
Summary:
| 【Product name】：Anti-PLD3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：23646 | 【Swiss Prot】：Q8IV08 |
| 【Observed】：60kDa | |
| 【Tested applications】：IHC,ELISA,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human PLD3 | |
| 【Public Immunogen Range】：230-280/490aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity).May be important in myotube formation (PubMed:22428023).Plays a role in lysosomal homeostasis (PubMed:28128235).Involved in the regulation of endosomal protein sorting (PubMed:29368044).
Verified picture:
Western blot analysis with PLD3 antibody diluted at 1:2000;Lane: SH-SY5Y,U937,293T,HMC1,Mouse spleen,Mouse testis,Mouse lung,Mouse brain.
Immunohistochemistry of paraffin-embedded Human testis cancer with PLD3 antibody diluted at 1:100.