Anti-STIMATE Polyclonal Antibody
Cat: K113510P
Summary:
| 【Product name】：Anti-STIMATE Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：375346 | 【Swiss Prot】：Q86TL2 |
| 【Observed】：33kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human STIMATE | |
| 【Public Immunogen Range】：100-150/294aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Acts as a regulator of store-operated Ca2+ entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679, PubMed:26644574).SOCE is a Ca2+ influx following depletion of intracellular Ca2+ stores (PubMed:26322679).Acts by interacting with STIM1, promoting STIM1 conformational switch (PubMed:26322679).Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574).Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574).
Verified picture:
Western blot analysis with STIMATE antibody diluted at 1:2000;Lane: HEL.
Immunohistochemistry of paraffin-embedded Human testis cancer with STIMATE antibody diluted at 1:100.