Anti-RRM2B Polyclonal Antibody
Cat: K113583P
Summary:
| 【Product name】：Anti-RRM2B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：50484 | 【Swiss Prot】：Q7LG56 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human RRM2B | |
| 【Public Immunogen Range】：1-180aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with RRM2B antibody diluted at 1:50.
Immunohistochemistry of paraffin-embedded Human thyroid cancer with RRM2B antibody diluted at 1:50.