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Anti-CENPU Polyclonal Antibody
Cat: K113595P
Summary:
【Product name】:Anti-CENPU Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:79682 【Swiss Prot】:Q71F23
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:Recombinant protein of human CENPU
【Public Immunogen Range】:1-177aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.
Verified picture:
Immunohistochemistry of paraffin-embedded Human prostate cancer with CENPU antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human testis cancer with CENPU antibody diluted at 1:100.