Anti-CENPU Polyclonal Antibody - SAlexa Fluor 594
Cat: K113595P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-CENPU Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79682 | 【Swiss Prot】：Q71F23 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human CENPU | |
| 【Public Immunogen Range】：1-177aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.
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